GNG7 — G protein subunit gamma 7
GNG7 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GNG7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B cell identity B cell maturation | C12orf42, CD37, DRAM2, ITM2B, PRICKLE1, RBMS1, SAV1, TNFRSF13C | View in SCUBA |
| Smooth muscle cells | Netrin Guidance Signaling Development | MMP23B, NTN1, PFKP, PRKAR2B, QSOX1, TMTC2, TYRP1 | View in SCUBA |
About the gene
| Synonyms | FLJ00058 |
|---|---|
| Chromosome | 19: 2511219-2702694 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, RAS pathway related proteins |
| Molecular function | Transducer |
Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilization of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.