PFKP — Phosphofructokinase, platelet
PFKP belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PFKP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC electrophysiological machinery Gut motility | ADRB3, CAP2, CDCA7L, CSRP2, DTNA, GREM2, LGI1, LMO3 +5 more | View in SCUBA |
| Lymphatic endothelial | Actin Cytoskeletal Dynamics Cytoskeletal | ACTN1, BMAL2, NAV2, PIK3C2B, PRRC2C, SLC39A14, SYNJ2 | View in SCUBA |
| Macrophages | Oxidative Metabolic Program Mitochondrial & OxPhos | ACADM, CA2, CALM3, CAPG, COQ2, CSRP1, CSTB, DENND2D +29 more | View in SCUBA |
| Smooth muscle cells | Netrin Guidance Signaling Development | GNG7, MMP23B, NTN1, PRKAR2B, QSOX1, TMTC2, TYRP1 | View in SCUBA |
About the gene
| Synonyms | PFK-C, PFKF |
|---|---|
| Chromosome | 10: 3066333-3137718 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Allosteric enzyme, Kinase, Transferase |
| Biological process | Glycolysis |
Function
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.