SCUBA

RBMS1 — RNA binding motif single stranded interacting protein 1

RBMS1 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RBMS1's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsB cell identity
B cell maturation
C12orf42, CD37, DRAM2, GNG7, ITM2B, PRICKLE1, SAV1, TNFRSF13CView in SCUBA
CD4⁺ T cellsResting memory T cell
Immune regulation
ANXA1, CD300A, CDC14A, CYB561, DHRS3, DYNLT3, IL7R, MYADM +5 moreView in SCUBA
FibroblastsInflammatory Fibroblast Activation
Inflammatory
ADAM9, CALU, CLMP, CNN3, GLIPR1, ITGAV, MCRIP1, NAP1L1 +5 moreView in SCUBA
Gamma-delta T cellsChromatin Epigenetic Regulation
DNA/chromatin regulation
AEBP2, ARID1B, ATG12, ATXN2L, BRWD1, CSNK1G3, EHBP1L1, FBRS +18 more
Innate lymphoid cellsLymphocyte Apoptosis Regulation
Immune regulation
ANP32B, ARMCX3, CCDC69, CHD2, DHRS7, ELF1, FXYD5, GLIPR1 +14 moreView in SCUBA
Lymphatic endothelialChromatin Remodeling
DNA/chromatin regulation
BAZ2B, CHD9, ITFG1, JMJD1C, MICAL3, MPDZ, PACSIN2, PHKB +4 moreView in SCUBA
MacrophagesMonocyte-Mac Iron Transport
Iron metabolism
ARFIP1, BCL2L1, CDS2, CLPB, EHD4, GNB4, HAVCR2, IVNS1ABP +9 moreView in SCUBA
Mucosal-associated invariant T cellIL-18 Innate Activation
Inflammation
ADAM10, COLQ, IL18RAP, KIF5C, ME1, MYBL1, NEO1, P2RY14 +3 more
Smooth muscle cellsSMC focal adhesion
Migration & adhesion
ANXA6, ARMCX6, C1orf21, CD99, DNAJC1, HSBP1, KANK1, MORF4L2 +7 moreView in SCUBA

About the gene

SynonymsC2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1
Chromosome2: 160272151-160493807
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Molecular functionDNA-binding, RNA-binding
Biological processDNA replication

Function

Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.