AIP — Aryl hydrocarbon receptor interacting protein
AIP belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AIP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Proteostasis OxPhos Housekeeping | ARPC1B, ATP6V1F, C4orf48, CHMP2A, IL2RG, NDUFA13, NDUFB10, PPP1R7 +6 more | View in SCUBA |
| CD8⁺ T cells | RNA Processing Mixed RNA processing & translation | CALM1, EZR, FUBP1, HNRNPA2B1, HNRNPH3, LCP1, LRRFIP1, MOB1A +8 more | View in SCUBA |
| Innate lymphoid cells | Ubiquitin Stress Response Stress | AK2, AP2A1, ARMC10, GPAA1, IAH1, NSFL1C, PHF5A, TRADD +2 more | View in SCUBA |
| Mucosal-associated invariant T cell | ER Glycosylation & Ubiquitin Protein processing & ER | ALDOA, ATP5MG, COX6A1, COX6B1, ELOB, FIS1, GAPDH, KRTCAP2 +9 more |
About the gene
| Synonyms | ARA9, FKBP16, FKBP37, XAP2 |
|---|---|
| Chromosome | 11: 67468174-67491154 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
Function
May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. Cellular negative regulator of the hepatitis B virus (HBV) X protein
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.