HMG20B — High mobility group 20B
HMG20B belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HMG20B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | TCR Vesicular Trafficking TCR Signaling | ARL2BP, ARL8A, ARRDC1, C18orf32, CCDC92, CD3D, CD3G, CD99 +14 more | |
| Macrophages | MMP-driven ECM Remodeling ECM remodeling | A4GALT, ACP5, ASB2, ASMTL, ATP6V0D2, BID, CFP, CPOX +12 more | View in SCUBA |
About the gene
| Synonyms | BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL |
|---|---|
| Chromosome | 19: 3572777-3579088 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | Chromatin regulator, DNA-binding |
| Biological process | Cell cycle, Transcription, Transcription regulation |
Function
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.