HOXB2 — Homeobox B2
HOXB2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HOXB2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Immune Regulation Immune regulation | ADAT2, AFTPH, C2CD4B, CDKL2, CPEB4, DDHD1, FAM53B, FAS +10 more | View in SCUBA |
| Endothelial | IL-27 Receptor Signaling Inflammation | CCND3, CDC37, IL27RA, KL, MMP15, NDUFA12, SPARCL1, TMEM243 | View in SCUBA |
| Innate lymphoid cells | NK Receptor Signaling Cytotoxicity | B2M, CD48, CLEC2B, DCK, FCER1G, FKBP11, GPR108, HLA-A +12 more | View in SCUBA |
About the gene
| Synonyms | HOX2, HOX2H |
|---|---|
| Chromosome | 17: 48540894-48545109 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | Developmental protein, DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.