HRAS — HRas proto-oncogene, GTPase
HRAS belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HRAS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Rho-Actin Remodeling Cytoskeletal | ANAPC11, ARPC2, ARPC5, ATP6V0B, GNAI2, HNRNPH3, KIF5B, PDAP1 +9 more | View in SCUBA |
| Smooth muscle cells | Lipid Kinase Signaling Housekeeping | ABTB1, ARRDC4, CACNA1H, CBX7, CX3CL1, DGKD, DNTTIP2, FCHSD2 +10 more | View in SCUBA |
About the gene
| Synonyms | HRAS1 |
|---|---|
| Chromosome | 11: 532242-537321 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins |
| Molecular function | Hydrolase |
Function
Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.