GNAI2 — G protein subunit alpha i2
GNAI2 belongs to a gene co-expression module in 11 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GNAI2's module in each cell type
About the gene
| Synonyms | GIP, GNAI2B |
|---|---|
| Chromosome | 3: 50226292-50259362 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Human disease related genes, Predicted intracellular proteins |
| Molecular function | Transducer |
| Biological process | Cell cycle, Cell division |
Function
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division. Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.