SCUBA

KIF5C — Kinesin family member 5C

KIF5C belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

KIF5C's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsActivated Effector ISG
Anti-viral
GOLGA7B, KIT, MAP2K6, MVB12B, NMUR1, PLCG1, PLOD3, POC1B +8 moreView in SCUBA
Mucosal-associated invariant T cellIL-18 Innate Activation
Inflammation
ADAM10, COLQ, IL18RAP, ME1, MYBL1, NEO1, P2RY14, PARP8 +3 more

About the gene

SynonymsNKHC2
Chromosome2: 148875227-149026759
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins
Molecular functionHydrolase, Motor protein
Biological processTransport

Function

Microtubule-associated force-producing protein that may play a role in organelle transport. Has ATPase activity (By similarity). Involved in synaptic transmission. Mediates dendritic trafficking of mRNAs (By similarity). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.