KLHL6 — Kelch like family member 6
KLHL6 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KLHL6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Somatic Hypermutation B cell maturation | DEF8, EAF2, HMCES, LBR, OGG1, PHF6, PRPSAP2, RFC1 +3 more | View in SCUBA |
| Gamma-delta T cells | Hypoxia Tissue Adaptation Tissue residence | ABCB1, ADAMTS17, ANKRD28, CCRL2, EPAS1, FAM3C, LDLRAD4, PHTF1 +10 more |
About the gene
| Synonyms | FLJ00029 |
|---|---|
| Chromosome | 3: 183487551-183555706 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Involved in B-lymphocyte antigen receptor signaling and germinal center formation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.