LPAR6 — Lysophosphatidic acid receptor 6
LPAR6 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LPAR6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Interferon response Anti-viral | ACBD5, AQP3, BTN2A1, BTN3A2, BTN3A3, CISH, EIF2AK2, ERAP2 +23 more | View in SCUBA |
| Endothelial | Capillary Endothelial Identity Endothelial cell development | ATOH8, AVPR2, BTNL9, C1QTNF9, CD300LG, CD34, CNFN, FAM13C +10 more | View in SCUBA |
| Macrophages | Stress Response Transcription Stress | AHR, C11orf96, CBX6, FAM110A, FN3K, GADD45A, LACC1, MKNK2 +8 more | View in SCUBA |
| Monocytes | ER Stress Response Stress | CALR, CSTB, CTNND1, HSP90B1, M6PR, MRPS6, PDIA6, PRDX1 +3 more | View in SCUBA |
| Mucosal-associated invariant T cell | Mucosal MAIT Homing migration & adhesion | BLK, BRD9, CCR6, DSEL, ERN1, FUT7, LGALS3, LST1 +5 more |
About the gene
| Synonyms | P2RY5, P2Y5 |
|---|---|
| Chromosome | 13: 48389567-48444704 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.