NKX2-3 — NK2 homeobox 3
NKX2-3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NKX2-3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Barrier Homeostasis migration & adhesion | AFDN, CD2AP, CLEC3B, ENPP2, IFNGR1, IL6R, ITGB4, JAM2 +11 more | View in SCUBA |
| Smooth muscle cells | Matrix Crosslinking Activation ECM remodeling | ADAM19, COL23A1, FOXF1, LOXL2, PLPP1, RCN1, VCAN | View in SCUBA |
About the gene
| Synonyms | CSX3, NKX2.3, NKX2C, NKX4-3 |
|---|---|
| Chromosome | 10: 99532942-99536524 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Transcription factor
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.