FOXF1 — Forkhead box F1
FOXF1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FOXF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Quiescence Identity Endothelial cell development | CCDC69, CLIC2, CLSTN3, CPD, EPB41L4A, FZD4, IGFBP7, KCNE4 +7 more | View in SCUBA |
| Fibroblasts | Telocyte Identity Program Developmental | ADGRL3, ANKRD50, ARHGAP28, CLSTN2, FBLN7, LAMA4, PDIA5, PREX2 +10 more | View in SCUBA |
| Pericytes | Pericyte Identity Developmental | ADAMDEC1, EDIL3, EMID1, IL1R1, LRP1, LTBP4, MXRA5, NR2F1 +2 more | View in SCUBA |
| Smooth muscle cells | Matrix Crosslinking Activation ECM remodeling | ADAM19, COL23A1, LOXL2, NKX2-3, PLPP1, RCN1, VCAN | View in SCUBA |
About the gene
| Synonyms | FKHL5, FREAC1 |
|---|---|
| Chromosome | 16: 86510527-86515422 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | Activator, DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Probable transcription activator for a number of lung- specific genes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.