NQO2 — N-ribosyldihydronicotinamide:quinone reductase 2
NQO2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NQO2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | NRF2 Oxidative Stress Stress | ACOT9, AHRR, ARMC9, BASP1, CARD19, CCDC71L, CD226, CLDND1 +27 more | View in SCUBA |
About the gene
| Synonyms | DHQV, DIA6, NMOR2, QR2 |
|---|---|
| Chromosome | 6: 2987987-3019755 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.