OTOP2 — Otopetrin 2
OTOP2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
OTOP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Surface colonocyte transport Absorption | CA4, CD46, CITED1, CLCN1, DOCK4, GSN, HSPB1, ITM2C +4 more | View in SCUBA |
About the gene
| Chromosome | 17: 74922950-74933912 |
|---|---|
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Transporters |
| Molecular function | Ion channel |
| Biological process | Hydrogen ion transport, Ion transport, Transport |
Function
Proton-selective ion channel open at neutral pH. Actives at neutral and alkaline extracellular pH, likely participates in some alkali-related physiological activities
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.