PARD6G — Par-6 family cell polarity regulator gamma
PARD6G belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PARD6G's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | S-phase Proliferation Cell cycle | ANKRD9, BCL6, COPS3, DCXR, ERRFI1, GMNN, GOLIM4, MTHFD2 +6 more | |
| Lymphatic endothelial | Anticoagulant Barrier endothelial development | AP2A2, ERICH1, JUP, KBTBD11, MMRN1, MYCT1, TFPI, TIMP3 | View in SCUBA |
About the gene
| Synonyms | PAR-6G, PAR6gamma |
|---|---|
| Chromosome | 18: 80157232-80247514 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division |
Function
Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.