MYCT1 — MYC target 1
MYCT1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MYCT1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Lymphatic endothelial | Anticoagulant Barrier endothelial development | AP2A2, ERICH1, JUP, KBTBD11, MMRN1, PARD6G, TFPI, TIMP3 | View in SCUBA |
| Pericytes | Vascular Barrier Integrity Migration & adhesion | C1orf115, FAM107A, GIMAP1, GIMAP4, GIMAP7, ITGB4, JAM2, NRN1 +2 more | View in SCUBA |
About the gene
| Synonyms | FLJ21269, MTLC |
|---|---|
| Chromosome | 6: 152697897-152724569 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.