GOLIM4 — Golgi integral membrane protein 4
GOLIM4 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GOLIM4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cytotoxic effector Cytotoxicity | ADAP1, ALOX5AP, AOAH, CD244, CMIP, CPNE7, CRTAM, DAPK2 +15 more | View in SCUBA |
| CD8⁺ T cells | Proliferating CD8 T cell Cell cycle | AHI1, ARL3, CDK6, SLC7A5, SQLE, TNIP3, TNS3, VCAM1 | View in SCUBA |
| Endothelial | ER-Golgi Trafficking Protein processing & ER | ATL3, DIAPH2, ECE1, EID1, KTN1, MAGT1, PGK1, SHISA5 +4 more | View in SCUBA |
| Enterocytes | Colonocyte differentiation TFs Chromatin regulation & transcription | AGAP1, ATXN1, DENND1B, DOCK5, GRAMD2B, HNF4G, JMJD1C, LCORL +7 more | View in SCUBA |
| Gamma-delta T cells | S-phase Proliferation Cell cycle | ANKRD9, BCL6, COPS3, DCXR, ERRFI1, GMNN, MTHFD2, OVCA2 +6 more | |
| Macrophages | Myeloid Innate Signaling Innate immunity | ADCY7, ARHGAP18, BMP2K, C3AR1, C6orf62, CD46, CD84, CLTC +34 more | View in SCUBA |
About the gene
| Synonyms | GIMPC, GOLPH4, GPP130, P138 |
|---|---|
| Chromosome | 3: 168008689-168095924 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | Transport |
Function
Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.