PHF11 — PHD finger protein 11
PHF11 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PHF11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Interferon response Anti-viral | ACBD5, AQP3, BTN2A1, BTN3A2, BTN3A3, CISH, EIF2AK2, ERAP2 +23 more | View in SCUBA |
| Gamma-delta T cells | EOMES Effector Program T cell maturation | AGK, ANKZF1, ATG16L2, C6orf120, CARD8, CBX1, CDK5RAP3, CENPT +25 more | |
| Macrophages | Antiviral ISG Response Antiviral | ADAR, APOL6, ARID5A, CLEC7A, DDX60, DTX3L, EIF2AK2, ERICH1 +29 more | View in SCUBA |
| Mucosal-associated invariant T cell | Type I Interferon Inflammation | DDX60, DDX60L, DTX3L, EIF2AK2, EPSTI1, GBP2, GBP4, HERC5 +18 more |
About the gene
| Synonyms | BCAP, IGER, NY-REN-34 |
|---|---|
| Chromosome | 13: 49495610-49528981 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Activator |
| Biological process | Transcription, Transcription regulation |
Function
Positive regulator of Th1-type cytokine gene expression
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.