REEP1 — Receptor accessory protein 1
REEP1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
REEP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC contractility Gut motility | BEX1, BTC, DES, HACD1, HSPB7, IL17B, KCNMA1, LDB3 +7 more | View in SCUBA |
| Lymphatic endothelial | Lymphangiogenesis ECM endothelial development | ARHGAP18, CEP68, CFI, DIPK2B, EGFL7, ELK3, ELN, FLT4 +10 more | View in SCUBA |
| Smooth muscle cells | Muscle Energy Metabolism Mitochondrial & OxPhos | ANP32B, HACD1, HEY2, MAP3K20, MRPS6, PIP5K1B, PNRC2, PPP1R1A +4 more | View in SCUBA |
About the gene
| Synonyms | C2orf23, FLJ13110, SPG31, Yip2a |
|---|---|
| Chromosome | 2: 86213993-86338083 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
Required for endoplasmic reticulum (ER) network formation, shaping and remodeling; it links ER tubules to the cytoskeleton. May also enhance the cell surface expression of odorant receptors. May play a role in long-term axonal maintenance.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.