EGFL7 — EGF like domain multiple 7
EGFL7 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EGFL7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Interferon Stimulated Inflammatory | BST2, IFITM3, LKAAEAR1, MGST3, NPDC1, PRDX1, VAMP5 | |
| Lymphatic endothelial | Lymphangiogenesis ECM endothelial development | ARHGAP18, CEP68, CFI, DIPK2B, ELK3, ELN, FLT4, KCNN3 +10 more | View in SCUBA |
About the gene
| Synonyms | ZNEU1 |
|---|---|
| Chromosome | 9: 136658856-136672678 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | Developmental protein |
| Biological process | Angiogenesis, Cell adhesion, Differentiation |
Function
Regulates vascular tubulogenesis in vivo. Inhibits platelet- derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.