S100A14 — S100 calcium binding protein A14
S100A14 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
S100A14's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | S100 Calcium Signaling Stress | CIB1, CLDN7, CLTB, GUK1, MYL12B, MYL6, RHOC, S100A11 +4 more | View in SCUBA |
About the gene
| Synonyms | BCMP84, S100A15 |
|---|---|
| Chromosome | 1: 153614255-153616986 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Biological process | Apoptosis |
Function
Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.