TMCO3 — Transmembrane and coiled-coil domains 3
TMCO3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMCO3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | ER Targeting ERAD Protein processing & ER | AP3S1, ARFGAP3, ARMCX3, HM13, KCNK6, PRRC1, SELENOS, SRPRA +1 more | View in SCUBA |
| Macrophages | Phagocytic Endolysosomal Lysosomal & pahgocytosis | ABHD2, ACTN4, AP3S1, ARF6, ATP6V1B2, CD151, CERS2, CNIH1 +27 more | View in SCUBA |
| Monocytes | Autophagy Initiation Lysosomal & pahgocytosis | AAK1, AGFG1, ARID3B, FHIP2A, PHC2, PTK2B, RIOK3, TRABD +1 more | View in SCUBA |
About the gene
| Synonyms | C13orf11, FLJ20623 |
|---|---|
| Chromosome | 13: 113491021-113554590 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Antiport, Ion transport, Transport |
Function
Probable Na(+)/H(+) antiporter
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.