TNFSF8 — TNF superfamily member 8
TNFSF8 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TNFSF8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Tfh IL21 help B cell help | APBB2, CDYL2, GDF7, HIF1A, IL21, KIAA1671, MFHAS1, MYB +6 more | View in SCUBA |
| Gamma-delta T cells | Effector Cytokine Secretion Inflammation | APBA2, ASPH, CCL3, CCL4, CMC1, CYRIA, DTHD1, DTNBP1 +25 more | |
| Natural Killer cells | Circadian Apoptotic Priming Stress | BBC3, CORO7, CTDP1, EML4, LDB2, NR1D2, OFD1, RNF125 +1 more | View in SCUBA |
About the gene
| Synonyms | CD153, CD30LG |
|---|---|
| Chromosome | 9: 114893343-114930595 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, CD markers, Predicted membrane proteins |
| Molecular function | Cytokine |
Function
Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.