SCUBA

BBC3 — BCL2 binding component 3

BBC3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

BBC3's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsp53 DNA-damage response
Stress
AEN, APOBEC3H, DDB2, FDXR, GZMH, PHLDA3, PKIG, RCAN2View in SCUBA
Natural Killer cellsCircadian Apoptotic Priming
Stress
CORO7, CTDP1, EML4, LDB2, NR1D2, OFD1, RNF125, SERPINE2 +1 moreView in SCUBA

About the gene

SynonymsJFY1, PUMA
Chromosome19: 47220822-47232766
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins
Biological processApoptosis

Function

Does not affect cell growth

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.