TSPOAP1 — TSPO associated protein 1
TSPOAP1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TSPOAP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Heat-shock response Stress | AHSA1, BAG3, CACYBP, CCDC117, DNAJB6, DYNLL1, FKBP4, GADD45G +5 more | View in SCUBA |
| Gamma-delta T cells | Mitochondrial RNA Processing Mitochondrial & OxPhos | ABR, DARS1, DENND1C, GTDC1, MRPS30, PDCD4, PMPCB, POLG +11 more | |
| Mucosal-associated invariant T cell | Metabolic Homeostasis Housekeeping | ADIPOR1, BIRC3, COQ10B, CREBRF, EIF1AX, GNAI3, H2AC20, KLF11 +10 more |
About the gene
| Synonyms | BZRAP1, KIAA0612, PRAX-1, RIM-BP1, RIMBP1 |
|---|---|
| Chromosome | 17: 58301228-58328795 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Transporters |
Function
Required for synaptic transmission regulation. It probably controls the recruitement of voltage- gated calcium channels to the presynaptic membrane, and modulates neurotransmitter release
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.