SCUBA

ZNF366 — Zinc finger protein 366

ZNF366 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ZNF366's module in each cell type

Cell typeModuleShares the module with
EndothelialEndothelial Lipid Signaling
migration & adhesion
A2M, ADGRG1, ARHGEF15, CNOT6L, CYYR1, DIP2B, HIP1R, PCDH1 +3 moreView in SCUBA
PericytesPericyte Contractile Tone
Cytoskeletal
CARD10, CARD8, EHD4, FAM110D, IL27RA, KANK3, LDB2, NOSTRIN +4 moreView in SCUBA

About the gene

SynonymsFLJ39796
Chromosome5: 72439903-72507410
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins, Transcription factors
Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Function

Has transcriptional repression activity. Acts as a corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.