NOSTRIN — Nitric oxide synthase trafficking
NOSTRIN belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NOSTRIN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Vasoactive GPCR Signaling Endothelial cell development | APLNR, BAIAP2L1, CALCRL, COPZ2, CYSLTR1, ETS2, FAM110D, FAM167B +10 more | View in SCUBA |
| Pericytes | Pericyte Contractile Tone Cytoskeletal | CARD10, CARD8, EHD4, FAM110D, IL27RA, KANK3, LDB2, PKP4 +4 more | View in SCUBA |
About the gene
| Synonyms | MGC20702 |
|---|---|
| Chromosome | 2: 168786539-168865514 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Endocytosis |
Function
Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.