AASDHPPT — Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
AASDHPPT belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AASDHPPT's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Glycosylation & trafficking Protein processing & ER | ABHD12, ACTR1A, ANKRD35, AP1S1, ARRDC1, ATF6B, ATG5, CDK19 +25 more | View in SCUBA |
| Innate lymphoid cells | JAK-STAT Cytokine Signaling Inflammation | ARHGAP9, CHURC1, CIDEB, CSK, DCAF7, DENND2D, EDEM2, EIF4EBP2 +23 more | View in SCUBA |
| Mucosal-associated invariant T cell | Lymphocyte Trafficking migration & adhesion | ANXA2, ARL14EP, ATP2A3, BIN1, BTN3A2, DGKZ, OSTC, PTP4A2 +8 more |
About the gene
| Synonyms | AASD-PPT, ACPS, CGI-80, LYS5 |
|---|---|
| Chromosome | 11: 106075501-106098699 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Transferase |
Function
Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.