SCUBA

ADAM23 — ADAM metallopeptidase domain 23

ADAM23 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ADAM23's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsCytotoxic effector
Cytotoxicity
CTSW, EMP3, FKBP2, IFITM2, IGFBP3, KLRG1, LYAR, PLP2 +11 moreView in SCUBA
EndothelialArterial EC Identity
Endothelial cell development
AGPAT2, CLDN5, ECHDC2, GOLGA8B, HHEX, LY6E, NDN, PERP +1 moreView in SCUBA
Glial cellsGlial Adhesion Identity
migration & adhesion
CADM4, CALU, DAG1, HMCN1, HMGN1, ITGA2, PTPRZ1, SDC3 +2 moreView in SCUBA

About the gene

SynonymsMDC3
Chromosome2: 206443532-206621127
Predicted locationIntracellular, Membrane, Secreted
Essential geneNo
Protein classPredicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Biological processCell adhesion

Function

May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.