CDA — Cytidine deaminase
CDA belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Mitophagy Stress Response Stress | C1QTNF12, CPNE2, FAM219A, FCN3, GSDMC, IGFBP3, INSR, MAP3K6 +7 more | View in SCUBA |
| Enterocytes | Endocytic nutrient uptake Absorption | CREB3L2, DAB2, DNAH7, EGLN3, LRP1, SLC43A2, SLC6A8 | View in SCUBA |
| Monocytes | Leukotriene-Alarmin Response Inflammatory | ALOX5AP, METTL9, MTARC1, PLBD1, QPCT, RFLNB, S100A12, TMEM38A | View in SCUBA |
| Neutrophils | Pentose Phosphate Pathway Housekeeping | ANXA3, ARPC2, CAP1, GYG1, HMGB2, LBR, PGD, SNX3 +1 more |
About the gene
| Synonyms | CDD |
|---|---|
| Chromosome | 1: 20589086-20618903 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase |
Function
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.