SLC43A2 — Solute carrier family 43 member 2
SLC43A2 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC43A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Venous EC Identity Endothelial cell development | ALDH1A1, ALDH3A2, ASGR1, ATP9A, BMP2K, DSP, FAM107B, KIAA1522 +12 more | View in SCUBA |
| Enterocytes | Endocytic nutrient uptake Absorption | CDA, CREB3L2, DAB2, DNAH7, EGLN3, LRP1, SLC6A8 | View in SCUBA |
| Hematopoietic progenitor cells | Lymphoid Progenitor Commitment Lymphcyte development | BASP1, CCR9, LRRC38, LSAMP, LZTFL1, MME, OSBPL3, SCN3A +3 more | |
| Innate lymphoid cells | NK Cytotoxic Effector Cytotoxicity | ACAA2, APIP, B4GALNT1, CAMK4, CCL5, CCNG2, CD247, CD3E +17 more | View in SCUBA |
| Macrophages | Lipid-Sensing Transcriptional Lipid metabolism | ANKLE2, BAIAP2, C19orf25, C1orf52, COX19, CWC25, DEDD2, DNTTIP2 +29 more | View in SCUBA |
| Monocytes | TREM1 Inflammatory Signaling Innate immunity | AGO2, AKAP12, ATP2B1, B3GNT5, BTG1, C17orf107, CHRNE, ERRFI1 +6 more | View in SCUBA |
| Neutrophils | Myeloid Inflammatory Activation Inflammatory | AQP9, CPD, FPR1, ITGAX, LITAF, MXD1, NABP1, NAMPT +5 more |
About the gene
| Synonyms | MGC34680 |
|---|---|
| Chromosome | 17: 1569268-1628886 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted membrane proteins, Transporters |
| Biological process | Amino-acid transport, Transport |
Function
Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine. The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.