SCUBA

VAMP5 — Vesicle associated membrane protein 5

VAMP5 belongs to a gene co-expression module in 12 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

VAMP5's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsImmunoproteasome IFN
Anti-viral
APRT, BATF, MT1X, MT2A, NIT2, PSMB9, PSME1, PSME2View in SCUBA
CD4⁺ T cellsInflammatory activation
Immune regulation
ACP5, B2M, CALCOCO1, CCNG2, CHST11, CORO1A, HLA-A, IL32 +10 moreView in SCUBA
EndothelialAngiogenic Endothelial Identity
Endothelial cell development
ADAMTSL2, ARHGAP29, COL13A1, CTNNB1, EDIL3, EML1, ETS1, EXOC3L1 +14 moreView in SCUBA
FibroblastsImmunoproteasome MHC-I
Inflammatory
B2M, BST2, EPSTI1, HLA-A, HLA-B, HLA-C, HLA-F, IFI27 +7 moreView in SCUBA
Glial cellsType I/II Interferon Response
Inflammation
GBP2, HLA-F, IFI6, IFIT3, ISG15, LY6E, PSMB8, PSMB9 +6 moreView in SCUBA
Hematopoietic progenitor cellsInterferon Stimulated
Inflammatory
BST2, EGFL7, IFITM3, LKAAEAR1, MGST3, NPDC1, PRDX1
Innate lymphoid cellsEndosomal Trafficking Signaling
Immune regulation
ARF1, CCDC85B, CKLF, COMMD8, FAM50A, GDE1, HAX1, IL27RA +16 moreView in SCUBA
Lymphatic endothelialOxidative Stress Response
Stress
AP2S1, APRT, ATOX1, C4orf3, FKBP1A, GADD45GIP1, GSTP1, RABAC1 +1 moreView in SCUBA
MacrophagesAntimicrobial Oxidative Defense
Antibacterial
ADAMDEC1, ALDOA, APOL3, CALHM6, CLEC10A, COX16, CPVL, DEFA5 +30 moreView in SCUBA
MonocytesImmunoproteasome Antigen Processing
Innate immunity
APOL1, APOL4, FBXO6, IFI27, IFI35, LGALS3BP, PSMB8, PSMB9 +5 moreView in SCUBA
PericytesVascular Junction Adhesion
Migration & adhesion
ABHD17A, CCDC85B, CDC37, ESAM, FYN, HECW2, PREX1, SELENON +2 moreView in SCUBA
Smooth muscle cellsIFN-gamma/NF-kB Response
Inflammation
ATP6V0B, CCDC71L, CFLAR, CHI3L2, EVA1B, GBP1, GBP2, HSPA8 +11 moreView in SCUBA

About the gene

Chromosome2: 85584431-85593406
Predicted locationMembrane
Essential geneNo
Protein classPredicted membrane proteins
Molecular functionDevelopmental protein
Biological processDifferentiation, Myogenesis

Function

May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.