FABP4 — Fatty acid binding protein 4
FABP4 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FABP4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Arterial EC Identity Endothelial cell development | CCDC71L, LAPTM5, MAP3K1, MDK, PCBD1, PMVK, RASSF4, SCNN1B +2 more | View in SCUBA |
| Fibroblasts | Homeostatic Fibroblast State Housekeeping | ADAM28, APOE, CCL13, CCL8, COLEC11, CRYBG3, ELANE, FABP5 +5 more | View in SCUBA |
| Macrophages | MMP-driven ECM Remodeling ECM remodeling | A4GALT, ACP5, ASB2, ASMTL, ATP6V0D2, BID, CFP, CPOX +12 more | View in SCUBA |
About the gene
| Synonyms | A-FABP, aP2 |
|---|---|
| Chromosome | 8: 81478419-81483236 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Biological process | Transport |
Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.