FEZ1 — Fasciculation and elongation protein zeta 1
FEZ1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FEZ1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Glial Cytoskeletal Homeostasis Cytoskeletal | ARL6IP5, CD99, CNP, CSRP1, RHEB, SCCPDH, TBCB, VWA1 | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB Effector Activation Inflammation | ADGRE5, BCL2A1, CCL20, CCL3, CCL3L3, CCL4, CCL4L2, DUSP10 +10 more |
About the gene
| Synonyms | UNC-76 |
|---|---|
| Chromosome | 11: 125442881-125592568 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Transport |
Function
May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.