ARL6IP5 — ADP ribosylation factor like GTPase 6 interacting protein 5
ARL6IP5 belongs to a gene co-expression module in 11 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARL6IP5's module in each cell type
About the gene
| Synonyms | DERP11, GTRAP3-18, HSPC127, JWA, PRAF3, Yip6b |
|---|---|
| Chromosome | 3: 69084937-69106092 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Transporters |
Function
Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity- dependent manner. Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.