VWA1 — Von Willebrand factor A domain containing 1
VWA1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
VWA1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Basement Membrane Assembly ECM remodeling | COL15A1, COL4A1, COL4A2, HSPG2, KIFC3, MGAT4A, NDST1, NOL4L +4 more | View in SCUBA |
| Glial cells | Glial Cytoskeletal Homeostasis Cytoskeletal | ARL6IP5, CD99, CNP, CSRP1, FEZ1, RHEB, SCCPDH, TBCB | View in SCUBA |
| Pericytes | Cytoskeletal Remodeling Cytoskeletal | ARHGAP18, F2RL3, FSCN1, IVNS1ABP, JUP, PASK, SEMA3F, TBCD | View in SCUBA |
| Smooth muscle cells | Basement Membrane Matrix ECM remodeling | ADH5, C4orf48, EFEMP2, FBXL7, MLXIP, MXRA8, PRNP, RTN4 | View in SCUBA |
About the gene
| Synonyms | FLJ22215, VWA-1, WARP |
|---|---|
| Chromosome | 1: 1434861-1442882 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Predicted intracellular proteins, Predicted secreted proteins |
Function
Promotes matrix assembly (By similarity). Involved in the organization of skeletal muscles and in the formation of neuromuscular junctions (Probable).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.