FOXS1 — Forkhead box S1
FOXS1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FOXS1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Pericytes | Pericyte Vascular Tone Developmental | ADAP2, CHCHD10, CSPG4, LINGO1, MCAM, MFGE8, PGF, PTGIR +3 more | View in SCUBA |
| Smooth muscle cells | Arteriolar Mural Cells Development | ESAM, GJA4, LINGO1, NDUFA4L2, NGF, OR51E1, OR51E2, PDGFA +3 more | View in SCUBA |
About the gene
| Synonyms | FKHL18, FREAC10 |
|---|---|
| Chromosome | 20: 31844303-31845604 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.