SYNJ2 — Synaptojanin 2
SYNJ2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SYNJ2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | EC Barrier Integrity Endothelial cell development | ABCB1, ADCY4, AQP3, ARHGAP31, CRYBG3, EPS8, FGR, FRYL +14 more | View in SCUBA |
| Gamma-delta T cells | PLZF Innate-like Effector T cell maturation | DUSP16, GALM, GRAMD1B, HNRNPLL, MKNK1, NIBAN1, PBX4, PERP +1 more | |
| Lymphatic endothelial | Actin Cytoskeletal Dynamics Cytoskeletal | ACTN1, BMAL2, NAV2, PFKP, PIK3C2B, PRRC2C, SLC39A14 | View in SCUBA |
| Monocytes | Secretory Vesicle Trafficking Vesicular traficking | ABHD17C, CTNNBL1, DHRS3, FAM20C, HMGA1, NRIP1, PCBP3, SEMA3F +1 more | View in SCUBA |
| Mucosal-associated invariant T cell | Tissue Residency Tissue residence | ACSL1, AMFR, CRACDL, DHX36, HES4, IRF8, ITGAE, LZTFL1 +8 more |
About the gene
| Synonyms | INPP5H |
|---|---|
| Chromosome | 6: 157981863-158099176 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase, RNA-binding |
| Biological process | Lipid metabolism |
Function
Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.