NIBAN1 — Niban apoptosis regulator 1
NIBAN1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NIBAN1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | PLZF Innate-like Effector T cell maturation | DUSP16, GALM, GRAMD1B, HNRNPLL, MKNK1, PBX4, PERP, SYNJ2 +1 more | |
| Lymphatic endothelial | Hippo-mTOR Quiescence endothelial development | BCAT1, FILIP1, FRMD6, KLHL3, LAMA4, PRR5L, SCN9A | View in SCUBA |
| Macrophages | SPP1 Tissue Remodeling ECM remodeling | BST1, CD52, CHI3L1, CHIT1, CSF1, FBP1, FGR, FN1 +19 more | View in SCUBA |
| Neutrophils | Mature Neutrophil Identity Developmental | ALPL, CR1, CRISPLD2, IL4R, PXN, SH3GLB1, ST3GAL4 |
About the gene
| Synonyms | C1orf24, FAM129A, GIG39, NIBAN |
|---|---|
| Chromosome | 1: 184790724-184974508 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins |
| Biological process | Stress response, Translation regulation |
Function
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.