LAMB2 — Laminin subunit beta 2
LAMB2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LAMB2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Lymphatic endothelial | ECM Remodeling TGFb migration & adhesion | CCDC80, CCND1, CHRDL1, CRIP1, CTSH, ECSCR, HS3ST1, IARS2 +8 more | View in SCUBA |
| Smooth muscle cells | ER-Golgi Secretory Protein processing & ER | ARL2, ATP2A2, BMP2, CD46, PLXND1, RNASEH2C, SPTB, YIF1A | View in SCUBA |
About the gene
| Synonyms | LAMS, NPHS5 |
|---|---|
| Chromosome | 3: 49121114-49133118 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Biological process | Cell adhesion |
Function
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.