GIMAP7 — GTPase, IMAP family member 7

GIMAP7 belongs to a gene co-expression module in 11 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

GIMAP7's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	GIMAP survival Immune regulation	ABLIM1, AKT3, ANKRD13D, ARL4C, C16orf54, CA5B, COPA, CRBN +16 more	View in SCUBA
CD8⁺ T cells	Effector Memory CD8 T cell maturation	CLDND1, DENND2D, GIMAP1, GIMAP4, GPR183, GZMK, ITM2C, KLRG1 +3 more	View in SCUBA
Endothelial	Arterial EC Homeostasis Endothelial cell development	APOL3, BMX, EXOC6, FAXDC2, FTH1, GABARAPL1, GAS6, GIMAP1 +10 more	View in SCUBA
Gamma-delta T cells	T Cell Survival T cell maturation	CASP1, CCDC107, CTU1, GEMIN7, GIMAP1, GIMAP2, GIMAP4, GIMAP5 +13 more
Innate lymphoid cells	NK Cytotoxic Regulation Cytotoxicity	ARHGAP30, BIN2, CAPN12, CHD9, CLK1, CTSC, CYB5B, DDX27 +29 more	View in SCUBA
Lymphatic endothelial	GIMAP mediated permeability Mitochondrial & OxPhos	AGTRAP, CCNI, GIMAP1, GIMAP4, GPR146, HEBP1, LYL1, PSMB9 +2 more	View in SCUBA
Macrophages	Inflammasome Oxidative Stress Inflammatory	ABI3, ADISSP, AKR1A1, ARHGDIB, ARPC1B, ASCL2, BLVRA, C1orf54 +33 more	View in SCUBA
Monocytes	GIMAP activation Housekeeping	FGD2, GIMAP1, GIMAP4, GIMAP6, GIMAP8, IRF2, NAGK, P2RY13 +2 more	View in SCUBA
Mucosal-associated invariant T cell	T cell Survival Regulation Immune regulation	ACTR3, C11orf98, CISH, FARSA, GIMAP1, GIMAP4, GIMAP5, MRPS18B +7 more
Natural Killer cells	NK Lymphocyte Survival Immune regulation	DENND2D, FGR, GIMAP1, GIMAP4, IL16, PTGDR, SLAMF6, TRAF3IP3	View in SCUBA
Pericytes	Vascular Barrier Integrity Migration & adhesion	C1orf115, FAM107A, GIMAP1, GIMAP4, ITGB4, JAM2, MYCT1, NRN1 +2 more	View in SCUBA

About the gene

Synonyms	IAN7, MGC27027
Chromosome	7: 150514872-150521073
Predicted location	Intracellular
Essential gene	No
Protein class	Predicted intracellular proteins

Function

The dimer has GTPase activity; the active site contains residues from both subunits

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.