EXOC4 — Exocyst complex component 4
EXOC4 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EXOC4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | mTOR-Exocyst Signaling TCR Signaling | ANKRD36C, ARFGEF1, CGGBP1, CTC1, DOCK11, EXOC1, FRYL, GSK3B +12 more | |
| Lymphatic endothelial | Polarized Vesicle Trafficking migration & adhesion | ELMO1, EXOC6B, IMMP2L, L3MBTL4, LRBA, LRMDA, MYO9A, PARD3B +5 more | View in SCUBA |
| Macrophages | Golgi Vesicle Trafficking Vesicular traficking | ARMH3, ATG7, CCDC91, CDK17, CLASP1, COG5, COMMD10, COP1 +24 more | View in SCUBA |
| Mucosal-associated invariant T cell | Calcium Signal Integration TCR Signaling | ANKRD44, ARB2A, CAMK2D, DOCK10, ELMO1, FCHSD2, FNDC3A, FOXN3 +20 more | |
| Neutrophils | General Homeostatic Regulation Housekeeping | ARID2, FBXL17, LARP4B, MCU, MGAT5, RAD51B, RASA1 |
About the gene
| Synonyms | KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p |
|---|---|
| Chromosome | 7: 133253073-134066589 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Transporters |
| Biological process | Exocytosis, Protein transport, Transport |
Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.