PTX3 — Pentraxin 3
PTX3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PTX3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Inflammatory Fibroblast Activation Inflammatory | ATP2A2, BAMBI, C5AR2, CRISPLD2, CSNK1E, CTNNB1, DLC1, ETS2 +11 more | View in SCUBA |
| Glial cells | NF-κB/IFN Inflammatory Inflammation | BIRC3, CTSS, CXCL10, CXCL2, CXCL9, FDCSP, HAPLN3, ICAM1 +4 more | View in SCUBA |
About the gene
| Synonyms | TNFAIP5, TSG-14 |
|---|---|
| Chromosome | 3: 157436850-157443633 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted secreted proteins |
Function
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.