CRISPLD2 — Cysteine rich secretory protein LCCL domain containing 2
CRISPLD2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CRISPLD2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Inflammatory Fibroblast Activation Inflammatory | ATP2A2, BAMBI, C5AR2, CSNK1E, CTNNB1, DLC1, ETS2, F2RL3 +11 more | View in SCUBA |
| Monocytes | p38 MAPK Signaling Inflammatory | CREB5, FBXL5, LBR, LRRK2, MAPK14, MEGF9, NFE2, NLRP12 +5 more | View in SCUBA |
| Neutrophils | Mature Neutrophil Identity Developmental | ALPL, CR1, IL4R, NIBAN1, PXN, SH3GLB1, ST3GAL4 | |
| Pericytes | Pericyte Inflammatory Activation Inflammatory | BATF3, FILIP1L, KCNJ8, MARCKS, PAG1, PDGFA, RHOBTB3, RHOQ +3 more | View in SCUBA |
| Smooth muscle cells | ER Chaperone/UPR Protein processing & ER | CALR, FBLIM1, HIF1A, HSP90B1, HSPA5, IL6ST, OSMR, PCOLCE +3 more | View in SCUBA |
About the gene
| Synonyms | DKFZP434B044, LCRISP2, LGL1 |
|---|---|
| Chromosome | 16: 84819985-84920768 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted secreted proteins |
Function
Promotes matrix assembly
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.