RALGAPA2 — Ral GTPase activating protein catalytic subunit alpha 2
RALGAPA2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RALGAPA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Angiogenic Metabolic Adaptation Endothelial cell development | BLVRB, DAAM1, HMGN3, LARP6, PCBP2, POLE4, PRKAG2, PRPSAP1 +2 more | View in SCUBA |
| Enterocytes | Long-gene intronic signal Technical artifact | ASCC3, CASK, KCNQ1, LGR4, MAP3K5, MECOM, MID1, PPP1R9A +5 more | View in SCUBA |
| Mucosal-associated invariant T cell | Immune Synapse Signaling TCR Signaling | APC, ARHGAP26, ASXL2, CD46, CPSF2, DOCK8, EEA1, EIF4G3 +21 more | |
| Neutrophils | Actin Cytoskeletal Remodeling Cytoskeletal | ACAP2, ARHGAP15, COP1, CUX1, DOCK8, DPYD, KDM2A, MED13L +9 more |
About the gene
| Synonyms | AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2 |
|---|---|
| Chromosome | 20: 20389530-20712644 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins |
| Molecular function | GTPase activation |
Function
Catalytic subunit of the heterodimeric RalGAP2 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.