SAMD11 — Sterile alpha motif domain containing 11
SAMD11 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SAMD11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Inflammatory TF Response Inflammatory | ADAMTS4, CEBPD, CMIP, FOSL2, KLF9, MAT2A, NR4A1, NR4A2 +2 more | View in SCUBA |
| Glial cells | BMP-SMAD Signaling Neroprotection | A2M, AQP1, ARC, CAPS, CRLF1, GDNF, ID1, ID3 +3 more | View in SCUBA |
About the gene
| Synonyms | MGC45873 |
|---|---|
| Chromosome | 1: 923923-944575 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, essential for establishing rod photoreceptor cell identity and function by silencing nonrod gene expression in developing rod photoreceptor cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.