SLC41A2 — Solute carrier family 41 member 2
SLC41A2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC41A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Treg regulation Immune regulation | BCAS3, CDK14, CEBPA, CLNK, CNIH1, COL9A2, CPA5, FCRL3 +8 more | View in SCUBA |
| Enterocytes | Epithelial junction polarity Migration & adhesion | CXADR, FRMD3, IL13RA1, KIF3B, MARVELD3, NEDD9, PTPRD, RAB6A +5 more | View in SCUBA |
| Macrophages | Alternative Activation Lipid Lipid metabolism | ACSL1, ADCY3, AGFG1, ARHGEF10L, ARID5B, ATP2B4, BCL6, CCL13 +24 more | View in SCUBA |
About the gene
| Synonyms | DKFZP434K0427 |
|---|---|
| Chromosome | 12: 104801801-104958744 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Ion transport, Transport |
Function
Acts as a plasma-membrane magnesium transporter. Can also mediate the transport of other divalent metal cations in an order of Ba(2+) > Ni(2+) > Co(2+) > Fe(2+) > Mn(2+) (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.