SLC6A6 — Solute carrier family 6 member 6
SLC6A6 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC6A6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | CD4 Lineage Identity T cell development | ACAA1, AGPAT3, ASCC3, ATF2, KIFAP3, KXD1, NEK7, PARP4 +6 more | View in SCUBA |
| Endothelial | Inflammatory Angiogenic Activation Inflammation | ALPL, APOL4, ASAP2, CALM1, COMMD2, FAT4, PDGFB, PLS3 +4 more | View in SCUBA |
| Macrophages | Osmotic Stress Response Stress | ANKRD28, BZW1, CD109, CXCL8, CYB5R4, CYTIP, DUSP4, EMP3 +25 more | View in SCUBA |
About the gene
| Synonyms | TAUT |
|---|---|
| Chromosome | 3: 14402576-14489349 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters |
| Biological process | Neurotransmitter transport, Symport, Transport |
Function
Mediates sodium- and chloride-dependent transport of taurine. Mediates transport of beta-alanine. Can also mediate transport of hypotaurine and gamma-aminobutyric acid (GABA) (By similarity). Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.