SUGT1 — SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
SUGT1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SUGT1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Protein/ER secretory machinery Protein processing & ER | ACTR2, ATP5IF1, ATP5ME, BAZ1B, CMC2, CNPY2, COMMD3, COPZ1 +16 more | View in SCUBA |
| Gamma-delta T cells | RNA Binding/Splicing RNA processing & translation | AIMP1, ATP11B, C1orf43, CCT2, DEDD2, DGKD, ENSA, ENY2 +18 more | |
| Innate lymphoid cells | NK Cytokine Signaling Immune regulation | BORCS7, C6orf62, DDX18, IER3, LMO4, MAT2A, NSUN6, PGGHG +3 more | View in SCUBA |
About the gene
| Synonyms | SGT1 |
|---|---|
| Chromosome | 13: 52652709-52700909 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Biological process | Ubl conjugation pathway |
Function
May play a role in ubiquitination and subsequent proteasomal degradation of target proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.